How to test a vaccine: A focus on CBPP

Angela Makumi, Noah Okumu, and Elise Schieck
How to test a vaccine: A focus on CBPP

Description

  • Testing novel vaccine candidates is a critical step in the development of modern vaccines.
  • A good reproducible challenge model is needed to test vaccines  or the control of CBPP
  • A good challenge model will test for the quality and quantity of the immune response, identify the optimal route of delivery and formulation, determine protection from infection and disease transmission, and evaluate the safety and toxicity of the vaccine formulation
  • Current challenge models include in contact which takes a longer period and intubation.
  • Other challenge models need to be investigated such as the use of newer nebulizers.

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