African swine fever virus challenge models to test vaccine efficacy

Hanneke Hemmink, Salima Mushtaq, Rose Ojuok, Christine Mutisya, Tore Tollersrud, Anna Lacasta
African swine fever virus challenge models to test vaccine efficacy

Description

African swine fever virus (ASFV) causes an acute hemorrhagic disease with up to 100% mortality in infected pigs. In sub-Saharan Africa ASFV is  endemic and multiple ASFV strains can circulate simultaneously. Live-attenuated ASFV vaccines are generally effective against homologous ASFV strains. Vaccines may not protect against more distant ASFV strains.

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