Surveying Salmonella antigens for use in a bacteriophage-based vaccine enabling homologous and heterologous protection and colonization-inhibition effect in poultry

Description

Description

Objectives

• Identifying antigens targeting different Salmonella enterica serovars from different species of poultry such as broilers, layers and indigenous chicken.

• Displaying these antigens targeting the different serovars as part of a virus (bacteriophage) nanoparticle structure or vesicles in order produce better sustainable multivalent vaccines that will elicit mucosal and systemic immune responses.

• Testing the oral route of administration as this is desirable because it offers a relatively simple means of mass vaccination

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