Clinical trials to develop a subunit vaccine for contagious bovine pleuropneumonia in Kenya



Objectives :

1. Reis olatio n of a virulent strain – in vivo passage of Mmm strain Afade (ILRI)

2. Development of a novel challenge model using a nebulizer fitted with a mask (ILRI and KALRO)

3. Process development and production of a scalable vaccine antigen production (KALRO, MERCK, VIDO)

4. On-Station Efficacy Trial (KALRO)

5. Tr a n s m i s s i o n  t r i a l ( K A L R O )


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