Poultry production is a critical livelihood activity in Uganda but is associated with imprudent use of antibiotics primarily for prophylaxis, growth promotion and protection of livelihoods. This misuse is a key driver of antibiotic resistance, undermining antibiotic efficacy and adversely affecting public and animal health, welfare, and productivity. Technological interventions such as improved animal husbandry practices and enhanced biosecurity are effective in reducing antibiotic use. However, these measures require significant behavioral changes. Using the concept of nudging from behavioral economics, we detail the co-creation of behavioral nudges to reduce antibiotic use in semi-intensive poultry production in peri-urban Uganda.